Abstract

Alumina has been widely used in biomedical applications due to its superior chemical, mechanical, and wear properties, and exhibits good biocompatibility. However, its limited use in hip and knee replacement applications is due to its low fracture toughness and bio-inertness. This study focuses on the synthesis and characterization of alumina nanopowders using a cost-effective sol-gel method using aluminum isopropoxide, as a precursor. The powders obtained after drying the gel in an oven were calcined at 800 oC for 1 hour in an electric furnace to produce the alumina nanopowder. During this process, parameters, such as temperature, pH, and stirring time, were carefully controlled to obtain the final product. X-ray diffraction, SEM, and TEM analysis were used to characterize the phases, composition, particle size, and morphology of alumina nanopowders. As a result, SEM and TEM analyses in conjunction with XRD data indicate that high-purity alumina nanopowders can be synthesized via the sol-gel process.

Keywords

Al2O3 nanoparticles, Sol-gel method, X-ray diffraction, Scanning Electron Microscope, TEM analysis,

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References

  1. D. Manyasree, P. Kiranmayi, R. Kumar, Synthesis, characterization and antibacterial activity of aluminium oxide nanoparticles, International Journal of Pharmacy and Pharmaceutical Sciences, 10(1), (2018) 32-35. https://doi.org/10.22159/ijpps.2018v10i1.20636
  2. P. Hassanpour, Y. Panahi, A. Ebrahimi‐Kalan, A. Akbarzadeh, S. Davaran, A.N. Nasibova, R. Khalilov, T. Kavetskyy, (2018). Biomedical applications of aluminium oxide nanoparticles. Micro & Nano Letters, 13(9), 1227–1231. https://doi.org/10.1049/mnl.2018.5070
  3. Z. Al-Timimi, Z.J. Tammemi, Nanoparticles of Alumina (Al2O3): An Overview and Their Applications in Medical Surgery. Journal of Nanomedicine, 4(2), (2021) 1046. http://meddocsonline.org/
  4. P.Thomas, S.Barnstorf, B.Summer, G.Willmann, B.Przybilla, Immuno-Allergological Properties Of Aluminium Oxide (Al2O3) Ceramics And Nickel Sulfate In Humans. Biomaterials, 24(6), (2002). 959–966. https://doi.org/10.1016/s0142-9612(02)00432-5
  5. C. Piconi, A. Tampieri, Oxide ceramics for biomedical applications. Encyclopedia of Materials: Technical Ceramics and Glasses, 3, (2021) 511-525. https://doi.org/10.1016/b978-0-12-803581-8.12101-0
  6. H.H. Al-Moameri, Z.M. Nahi, D.R. Rzaij, N.T. Al-Sharify, A review on the biomedical applications of alumina. Journal of Engineering and Sustainable Development, 24(5), (2020) 28-36. https://doi.org/10.31272/jeasd.24.5.5
  7. A. Udduttula, J.V. Zhang, P.G. Ren, (2019) Bioinert Ceramics for Biomedical Applications. In Biomedical Science and Technology Series (Wiley/Scrivener).
  8. D.F. Niero, O.R.K. Montedo, A.M. Bernardin, Synthesis and characterization of nano α-alumina by an inorganic sol–gel method. Materials Science and Engineering B, 280, (2022) 115690. https://doi.org/10.1016/j.mseb.2022.115690
  9. J. Konstanty, D. Tyrala, Particle Sizing and Surface Area Measurements: A comparative assessment of commercial air permeability and laser light diffraction instruments. Applied Sciences, 14(11), (2024) 4802. https://doi.org/10.3390/app14114802
  10. K. Agrawal, G. Singh, D. Puri, S. Prakash, Synthesis and characterization of hydroxyapatite powder by sol-gel method for biomedical application, Journal of Minerals & Materials Characterization & Engineering, 10(8), (2011) 727-734.
  11. A. Ulatowska-Jarza, D. Andrzejewski, K. Maruszewski, H. Podbielska, W. Strek, Advantages of sol-gel technologies for biomedical applications, In Optical and Imaging Techniques for Biomonitoring IV 3567.SIPE Digital Library, 3567, (1999) 50-58. https://doi.org/10.1117/12.339188
  12. R. Gupta, A. Kumar, Bioactive materials for biomedical applications using sol–gel technology. Biomedical Materials, 3(3), (2008) 034005. https://doi.org/10.1088/1748-6041/3/3/034005
  13. F. Ashrafi, S.A. Babanejad, A. Ghasemi, Synthesis of alumina nano powder using sol-gel method and chelate precursor, Asian Academic Research Journal of Multidisciplinary, 2, (2015) 2319-2801.
  14. M. Farahmandjou, N. Golabiyan, Synthesis and characterization of Alumina (Al2O3 ) nanoparticle prepared by simple by sol- gel method, International Journal of Bio-Inorganic Hybrid Nanomaterials, 5(1), (2016) 73-77.
  15. R. Rogojan, E. Andronescu, C. Ghitulica, B. S. Vasile, Synthesis and characterization of alumina nano-powder obtained by sol-gel method. UPB Buletin Scientific, Series B: Chemistry and Materials Science, 73(2), (2011) 67-76.
  16. S. Bhattacharyya, P.S. Behera, Synthesis and characterization of nano-sized α-alumina powder from kaolin by acid leaching process. Applied Clay Science, 146, (2017) 286–290. https://doi.org/10.1016/j.clay.2017.06.017
  17. W. Liu, X. Liu, P. Zhang, Z. Wang, X. Li, M. Hu, Nano-sized plate-like alumina synthesis via solution combustion. Ceramics International, 45(8), (2019) 9919–9925. https://doi.org/10.1016/j.ceramint.2019.02.034
  18. D. Mrabet, M. Vu, S. Kaliaguine, T. Do, A new route to the shape-controlled synthesis of nano-sized γ-alumina and Ag/γ-alumina for selective catalytic reduction of NO in the presence of propene. Journal of Colloid and Interface Science, 485, (2016) 144–151. https://doi.org/10.1016/j.jcis.2016.09.021
  19. R. Halder, S. Bandyopadhyay, Synthesis of fast sinterable oxygen deficient nano α−alumina & its optical properties. Journal of Alloys and Compounds, 735, (2017) 2092–2101. https://doi.org/10.1016/j.jallcom.2017.11.297
  20. K.M. Parida, A.C. Pradhan, J. Das, N. Sahu, Synthesis and characterization of nano-sized porous gamma-alumina by control precipitation method. Materials Chemistry and physics 113(1), (2009) 244-248.
  21. S. Said, S. Mikhail, M. Riad, Recent processes for the production of alumina nano-particles. Materials Science for Energy Technologies, 3, (2020) 344-363. https://doi.org/10.1016/j.mset.2020.02.001
  22. H. Yang, M. Liu, J. Ouyang., Novel synthesis and characterization of nanosized γ-Al2O3 from kaolin, Applied Clay Science, 47(3-4), (2010) 438-443. https://doi.org/10.1016/j.clay.2009.12.021